Abacavir + Lamivudine is a combination of two nucleoside reverse transcriptase inhibitors (NRTIs) used in the management of Human Immunodeficiency Virus (HIV) infection. This fixed-dose formulation improves treatment adherence by combining two active ingredients into a single tablet.
Both Abacavir and Lamivudine work by inhibiting reverse transcriptase, an enzyme essential for HIV replication. By blocking this enzyme, the medication helps reduce the viral load in the bloodstream and enhances immune system function.
This combination is typically used as part of a complete antiretroviral therapy (ART) regimen and is not a cure for HIV. However, consistent use can significantly reduce disease progression and lower the risk of HIV transmission.
Key Benefits:
- Effective suppression of HIV viral load
- Convenient fixed-dose combination for better compliance
- Supports immune system recovery
Important Safety Information:
- Screening for HLA-B*5701 is required before initiating therapy due to risk of hypersensitivity reaction associated with Abacavir
- Not recommended for patients with known hypersensitivity to either component
- Use with caution in patients with liver or kidney impairment
Storage Instructions:
Store at room temperature, away from heat, moisture, and direct sunlight.